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Can Wei Selected Research

Spermine

1/2022Transcriptomics Coupled to Proteomics Reveals Novel Targets for the Protective Role of Spermine in Diabetic Cardiomyopathy.
1/2021Spermine Protects Cardiomyocytes from High Glucose-Induced Energy Disturbance by Targeting the CaSR-gp78-Ubiquitin Proteasome System.
1/2021Spermine Regulates Immune and Signal Transduction Dysfunction in Diabetic Cardiomyopathy.
8/2020Exogenous spermine attenuates myocardial fibrosis in diabetic cardiomyopathy by inhibiting endoplasmic reticulum stress and the canonical Wnt signaling pathway.
5/2020[Spermine attenuates high glucose-induced myocardial fibrosis by regulating the cell cycle].
5/2020[Effect of exogenous spermine pretreatment on alleviating renal fibrosis in diabetic nephropathy mice and its related mechanism].
1/2020Exogenous spermine attenuates rat diabetic cardiomyopathy via suppressing ROS-p53 mediated downregulation of calcium-sensitive receptor.
9/2019[Exogenous spermine alleviates myocardial injury induced by hyperglycemia by inhibiting golgi stress].
1/2016Spermine inhibits Endoplasmic Reticulum Stress-induced Apoptosis: a New Strategy to Prevent Cardiomyocyte Apoptosis.
1/2016Exogenous spermine inhibits hypoxia/ischemia-induced myocardial apoptosis via regulation of mitochondrial permeability transition pore and associated pathways.
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Can Wei Research Topics

Disease

9Ischemia
08/2020 - 03/2012
8Diabetic Cardiomyopathies
01/2022 - 01/2015
7Fibrosis (Cirrhosis)
01/2022 - 08/2019
7Hypoxia (Hypoxemia)
06/2019 - 07/2013
6Infarction (Infarctions)
08/2020 - 03/2012
5Type 1 Diabetes Mellitus (Autoimmune Diabetes)
01/2021 - 01/2020
5Neoplasm Metastasis (Metastasis)
01/2019 - 01/2013
4Body Weight (Weight, Body)
01/2022 - 09/2019
4Neoplasms (Cancer)
01/2019 - 02/2013
3Hyperglycemia
01/2021 - 09/2019
3Renal Cell Carcinoma (Grawitz Tumor)
01/2018 - 01/2013
2Liver Diseases (Liver Disease)
11/2022 - 01/2021
2Liver Cirrhosis (Hepatic Cirrhosis)
11/2022 - 01/2022
2Inflammation (Inflammations)
02/2022 - 01/2021
2Pulmonary Hypertension
08/2019 - 06/2019
2Carcinogenesis
06/2015 - 02/2013
2Myocardial Infarction
01/2015 - 05/2013
2Reperfusion Injury
01/2014 - 07/2013
1Diabetic Angiopathies (Diabetic Angiopathy)
07/2022
1Pica (Geophagia)
02/2021
1Ischemic Stroke
08/2020
1Heart Diseases (Heart Disease)
08/2020
1Hypertrophy
08/2020
1Diabetic Nephropathies (Diabetic Nephropathy)
05/2020
1Myocardial Reperfusion Injury
08/2019
1Myocardial Ischemia (Ischemic Heart Diseases)
08/2019
1Vascular Remodeling
06/2019
1Prostatic Neoplasms (Prostate Cancer)
01/2019
1Kidney Neoplasms (Kidney Cancer)
01/2018
1Traumatic Brain Injuries (Traumatic Brain Injury)
01/2018
1Colorectal Neoplasms (Colorectal Cancer)
02/2017
1Vascular Diseases (Vascular Disease)
11/2015
1Atherosclerosis
11/2015

Drug/Important Bio-Agent (IBA)

11SpermineIBA
01/2022 - 01/2016
5Glucose (Dextrose)FDA LinkGeneric
07/2022 - 01/2020
5Proteins (Proteins, Gene)FDA Link
01/2021 - 01/2013
4Blood Glucose (Blood Sugar)IBA
01/2022 - 09/2019
3Streptozocin (Streptozotocin)FDA Link
01/2021 - 01/2020
3Reactive Oxygen Species (Oxygen Radicals)IBA
01/2016 - 07/2013
2wogonosideIBA
11/2022 - 01/2019
2Insulin (Novolin)FDA Link
01/2022 - 08/2020
2Dopamine Receptors (Dopamine Receptor)IBA
01/2021 - 07/2013
2Matrix Metalloproteinases (MMPs)IBA
01/2021 - 05/2020
2CreatinineIBA
01/2021 - 01/2016
2EnzymesIBA
08/2020 - 09/2019
2PolyaminesIBA
08/2020 - 01/2016
2CollagenIBA
08/2020 - 05/2020
2CalciumIBA
01/2020 - 08/2019
2Hydrogen Sulfide (Sulfide, Hydrogen)IBA
01/2019 - 04/2018
2Phosphotransferases (Kinase)IBA
01/2016 - 01/2013
2salicylhydroxamic acid (SHAM)IBA
05/2014 - 03/2012
2Dialysis SolutionsIBA
05/2013 - 03/2012
1FlavonoidsIBA
11/2022
1Therapeutic UsesIBA
11/2022
1Small Interfering RNA (siRNA)IBA
11/2022
1pifithrinIBA
11/2022
1Atorvastatin (Lipitor)FDA Link
02/2022
1Sorafenib (BAY 43-9006)FDA Link
01/2022
1Triglycerides (Triacylglycerol)IBA
01/2022
1DNA (Deoxyribonucleic Acid)IBA
02/2021
1MicroRNAs (MicroRNA)IBA
02/2021
1Nucleic AcidsIBA
02/2021
1Dopamine (Intropin)FDA LinkGeneric
01/2021
1Fibronectins (Fibronectin)IBA
01/2021
1AlbuminsIBA
01/2021
1Urea (Carbamide)FDA LinkGeneric
01/2021
13-n-butylphthalide (butylphthalide)IBA
08/2020
1glucose-regulated proteinsIBA
08/2020
1SpermidineIBA
08/2020
1AcetyltransferasesIBA
08/2020
1Activating Transcription Factor 4IBA
08/2020
1Ornithine Decarboxylase (Decarboxylase, Ornithine)IBA
08/2020
1CyclinsIBA
05/2020
1Aspartate Aminotransferases (Aspartate Transaminase)IBA
01/2020
1Alanine Transaminase (SGPT)IBA
01/2020
1mouse propeptide convertase 5IBA
01/2020
1Indicators and Reagents (Reagents)IBA
08/2019
1Calcium-Sensing ReceptorsIBA
06/2019
1CateninsIBA
01/2019
1SolutionsIBA
04/2018
1sodium bisulfide (NaHS)IBA
04/2018
1huaierIBA
01/2018
1HMGB1 Protein (HMG1)IBA
01/2018
1Epidermal Growth Factor (EGF)IBA
02/2017
1Sirtuin 2IBA
02/2017
1shikoninIBA
02/2017
1Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA
02/2017
1Troponin IIBA
01/2016
1Mitochondrial Permeability Transition PoreIBA
01/2016
1CobaltIBA
01/2016
1Receptor for Advanced Glycation End ProductsIBA
11/2015
1OsteoprotegerinIBA
11/2015
1p38 Mitogen-Activated Protein KinasesIBA
10/2015
1Mitogen-Activated Protein Kinase 3IBA
10/2015
1JNK Mitogen-Activated Protein KinasesIBA
10/2015
1Mechanistic Target of Rapamycin Complex 1IBA
06/2015

Therapy/Procedure

3Therapeutics
01/2018 - 01/2014
2Ischemic Postconditioning
01/2019 - 04/2014
1Intraperitoneal Injections
08/2020
1Chinese Traditional Medicine (Traditional Chinese Medicine)
01/2018